Cell Therapy | Advantages

The evolution of therapeutics from small molecules to macromolecular biologics has significantly improved modern medicine’s ability to treat complex diseases.  Our goal is to develop a next generation biologic treatment by harnessing the therapeutic potential of the human cell.  This future therapy will have the potential to overcome the limitations of current treatments.

1. Unique mechanism of action — Our therapy augments the body's ability to heal itself using allogeneic human adult bone marrow-derived somatic cells (hABM-SC).  These cells secrete a variety of pro-regenerative growth factors and cytokines which help to repair damaged tissue and reverse the disease process.  Once the cells have facilitated the natural repair mechanism, they are effectively eliminated by the body.
2. Non-immunogenic — Unlike currently marketed recombinant proteins, hABM-SC are non-immunogenic.  Preclinical data suggest that hABM-SC inhibit T-cell proliferation, resulting in a suppression of autoimmune response.
3. Non-differentiating cells — Unlike other cellular therapies, especially stem cell therapies, which have a propensity to differentiate into numerous tissue types, the risk of hABM-SC developing into undesirable foreign tissue is minimal.  In the course of the proprietary Neuronyx expansion process, hABM-SC lose the ability to differentiate, resulting in a product that is homogeneous, pure and consistent.  This is supported by data from numerous preclinical studies.
4. Efficient Production — Neuronyx has developed a manufacturing process that enables the production of enough cells to supply the entire predicted marketplace for a single indication using cells from a single human donor.  This method ensures consistency of the product, offering a significant advantage over competitive therapies which require the use of cells derived from dozens if not hundreds of discrete donors.
5. Multiple therapeutic applications — Rather than targeting a single receptor or protein -which only addresses a single component of disease - hABM-SC have the ability to secrete multiple therapeutically active cytokines to regulate complex biologic processes such as immunity, inflammation and tissue regeneration.  Our proprietary technology allows us to produce these cells efficiently and in large quantities for evaluation as medical therapies in numerous clinical applications.